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Endocrine Disruptors

"Endocrine disruptors" are a broad term for chemical substances that may disrupt the hormonal systems of humans and wildlife by mimicking or blocking the action of normal hormones. The best-known example is synthetic estrogens. DDT, dioxins, PCBs, and certain epoxy resins are among the chemicals that may act as endocrine system disruptors.
  
Endocrine Disruptors Research Initiative
Describes the coordination of U.S. federal government efforts to examine the hypothesis that there are chemicals present in the environment of humans and wildlife that, by virtue of their ability to interact with endocrine systems, are causing a variety of adverse health effects.
WWF Endocrine Disruptor Information
Papers and speeches on how hormone disruptors interfere with bio-chemical processes, and a suspected list of hormone disruptors.
Hormonally Active Agents in the Environment
1999 National Academy of Sciences report (1) examines the science behind the ominous prospect of "estrogen mimics" threatening health and well-being and (2) identifies research needs. Purchase book or read it online.
Endocrine Disrupting Substances in the Environment
Canadian Environmental Corps offers PDF file on this subject.
Environmental Toxins and Reproductive Health -- About.com
Information and internet links related to the reproductive effects of dioxins and other environmental toxins.
Introduction to Hormone Disrupting Chemicals
An introduction to the effects of hormone disrupting chemicals on man and the environment, and the response of governments and industry to this problem. Written for anyone interested in the subject. Includes internet links and other references.
Öko-Recherche
Analyses of material flows of chemicals in the environment, including endocrine-disrupting industrial chemicals.
Endocrine/Estrogen Letter
Newsletter and comprehensive set of endocrine disrupter links.
International POPs Elimination Network
IPEN works for the global elimination of persistent organic pollutants. Information on PCBs (polychlorinated biphenyls) including health effects, international, national and local policy efforts, elimination technology, and links to further research and resources.
e.hormone: At the Cutting Edge of Endocrine Disruptor Research.
Provide information about: upcoming conferences, the latest in research techniques and results, commentaries from distinguished scholars in the field, links to related news and stories.
Our Stolen Future
Provides updates about endocrine disruption created by man-made chemical contaminants that interfere with hormones in humans and wildlife.
Dioxin Facts
Chlorine Chemistry Council provides information regarding dioxins, their release into the environment, and their effects on human health.
Fox River Watch
Provides information on the PCB pollution of the Fox River, Green Bay, Wisconsin and Lake Michigan including research on PCBs, history, health effects, toxicity, sediment remediation, dredging, cleanup, and politics.
PCB Home Page at EPA
Provides information on Polychlorinated Biphenyls (PCB's). Background, resources and links to many topics.
National Toxicology Program Center for the Evaluation of Risks to Human Reproduction (CERHR)
Resource for the latest information about potentially hazardous effects of chemicals on human reproduction and development.
The Dioxin Home Page
Personal home page by Lewis A. Shadoff, Ph.D., discusses dioxins, furans, and similar toxic substances, including what they are and where they are found.
Thymus Atrophy
Abstract of study that investigated whether TCDD triggers apoptosis in thymocytes.
Weed Killer Deforms Sex Organs in Frogs, Study Finds
New York Times report on University of California study that found that male frogs exposed to very low doses of atrazine are deficient in testosterone and can develop multiple sex organs.
Dioxin Threat
A report on the technical and social implications of dioxin.
New Studies Confirm Dangers of Atrazine, a Widely Used Agricultural Weed-Killer
NRDC website describes research suggesting the atrazine is a carcinogen and causes sexual abnormalities in male frogs.
The Information Site on Endocrine Modulation
This conservative, industry/government funded site provides very cautious interpretations of scientific findings about endocrine disruption.
Coalition Opposed to PCB Ash in Monroe County, Indiana
Provides information concerning the problem related to PCB hazardous waste incinerator and landfill. Links to resources and research.
Endocrine Disrupters: Are Synthetic Hormones Causing Environmental Chaos?
Information from the Why Files about the endocrine system, effects of pesticides/PCBs/dioxins on wildlife and people, and prospects for action to resolve this concern.
OECD Endocrine Disruptors Assessment
Part of the OECD Test Guidelines Programme, focused on reaching international agreement on the testing and assessment of chemicals with respect to their endocrine disrupting potential.
Persistent Organic Pollutants (POPs)
These chemical substances persist in the environment, bioaccumulate through the food web, and pose a risk of causing adverse effects to human health and the environment. From the United Nations Environment Programme (UNEP).
Endocrine Disruption by Estrogenic Environmental Pollutants
Overview of a chapter by B. Rey de Castro from the book Environmental Medicine.
Endocrine Disruptors Low-Dose Peer Review
Report evaluating the low dose effects and dose response relationships for endocrine disrupting chemicals in mammalian species that relate to human health.
Questions and Answers About Dioxins and Food Safety
Discusses dioxins in the food chain.
Phthalates and Human Health: Demystifying the Risks of Plastic-softening Chemicals
Discusses human health concerns and public health benefits related to plasticizers, which are chemicals used to soften normally-rigid PVC, or polyvinyl chloride plastics.